Dapaglip 10mg 10pcs

Indications of Dapaglip 10mg Tablet

Dapaglip 10mg Tablet is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Pharmacology of Dapaglip 10mg Tablet

Dapagliflozin is a highly potent, selective, and reversible inhibitor of sodium-glucose cotransporter 2 (SGLT2) that improves glycemic control in patients with type 2 diabetes mellitus by reducing renal glucose reabsorption leading to urinary excretion of excess glucose (glucuronic).

Dapaglip 10mg Tablet Dosage & Administration 

5 mg orally once a day. May increase to 10 mg orally once a day in patients tolerating therapy with 5 mg and requiring additional glycemic control

Interaction

When insulin and insulin secretagogues, such as sulfonylureas, are used together, hypoglycemia might result. Rifampin causes a decrease in Cmax and AUC. Mefenamic acid increases Cmax and AUC. Dehydration and hypotension may be increased due to increased thiazide and loop diuretic effects. Pioglitazone.

Contraindications

Dapagliflozin propanediol or any of the excipients cause hypersensitivity. Renal impairment ranging from mild to severe; end-stage renal illness; active bladder cancer Lactation with pregnancy (second and third trimesters)

Side Effects

When insulin and insulin secretagogues, such as sulfonylureas, are used together, hypoglycemia might result. Rifampin causes a decrease in Cmax and AUC. Mefenamic acid increases Cmax and AUC. Dehydration and hypotension may be increased due to increased thiazide and loop diuretic effects. Pioglitazone.

Pregnancy & Lactation

Dapagliflozin propanediol or any of the excipients cause hypersensitivity. Renal impairment ranging from mild to severe; end-stage renal illness; active bladder cancer Lactation with pregnancy (second and third trimesters)

Precautions & Warnings

CV disease, history of hypotension, UTI, Children, Elderly. Unknown whether distributed in human breast milk; breastfeeding women should discontinue dapagliflozin or nursing taking into account the importance of the drug to the mother.

Storage Conditions

Keep the temperature below 30°C and away from light and moisture. Keep out of children's reach.